"Near forty years I have been Grand Maester of the Seven Kingdoms," Pycelle replied. "Under our good King Robert, and Aerys Targaryen before him, and his father Jaehaerys the Second before him, and even for a few short months under Jaehaerys's father, Aegon the Fortunate, the Fifth of His Name. I have seen more of illness than I care to remember, my lord. I will tell you this: Every case is different, and every case is alike. Lord Jon's death was no stranger than any other."

"His wife thought otherwise."

The Grand Maester nodded. "I recall now, the widow is sister to your own noble wife. If an old man may be forgiven his blunt speech, let me say that grief can derange even the strongest and most disciplined of minds, and the Lady Lysa was never that. Since her last stillbirth, she has seen enemies in every shadow, and the death of her lord husband left her shattered and lost."

"So you are quite certain that Jon Arryn died of a sudden illness?"

"I am," Pycelle replied gravely. "If not illness, my good lord, what else could it be?"

"Poison," Ned suggested quietly.

Pycelle's sleepy eyes flicked open. The aged maester shifted uncomfortably in his seat. "A disturbing thought. We are not the Free Cities, where such things are common. Grand Maester Aethelmure wrote that all men carry murder in their hearts, yet even so, the poisoner is beneath contempt." He fell silent for a moment, his eyes lost in thought. "What you suggest is possible, my lord, yet I do not think it likely. Every hedge maester knows the common poisons, and Lord Arryn displayed none of the signs. And the Hand was loved by all. What sort of monster in man's flesh would dare to murder such a noble lord?"