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They took a step further and once again Dr. Wagner kind of gave us a preview of this
他们还进了一步，Wagner医生之前也提到过
Now cultured in pools of serum that had been supplied by Dr. Hollis
这是在Hollis医生所提供血清中的培养结果
One was an African-American pool; one was white pool
前两个是非裔美国人和白人血清
And that's the amount of messenger RNA that was expressed in the African-American serum
这是非裔美国人血清中信使RNA表达的量
That's the amount that was expressed from the white serum
这是白人血清中的表达量
Now they said what's wrong with African-American serum?
他们问，非裔美国人血清是怎么回事？
Is there something genetically different about them?
其基因上是否有什么不同？
One thing we know is they don't have as much as vitamin D
非裔美国人没有那么多维生素D
So let's add 25D to the serum and see what happens and lo and behold, they rescued it
加入一些25D到血清看看，结果很好
How much vitamin D are we talking about?
有多少维生素D
The African-American pool had 22 nmol which is 9 ng/ml
非裔美国人血清中是22纳摩，也就是9纳克/毫升
We would all agree by any standard that that's a clearly set normal value, whereas a white pool had 78
所有人都相信，不管怎么看这是他们的正常值而白人血清中是78
That's still not 80 that's surely not 100 nm or 40 ng but it was a lot better than the African-American
远远没到100纳摩或40纳克，但比非裔美国人好多了
And that's what made a difference
这就是差别
and so these experiments showed that vitamin D is an essential mediator in the innate immune response definitively that serum 25D is the critical variable
这些实验决定性地显示，维生素D对免疫应答非常关键，血清25D是关键变量，
and at least some of the increased sensitivity to infection in vitamin D deficiency
至少维生素D缺乏者更容易患病
