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Now I want to show you a randomized controlled trial with respect to blood pressure
下面讲一个关于血压的随机试验
This was published in Germany. Now nine years ago
9年前发表于德国
I'm just amazed that nobody seems to know about it
我很惊讶，竟然没人知道它
A perfectly good journal, Clinical Endocrinology & Metabolism
临床内分泌代谢杂志，它其实很棒
148 older women double-blind randomized trial
148名老年妇女，双盲随机试验
The baseline 25D was below 50 nmol
基线25D低于50纳摩
It's kind of typical of what we would find in the US and they were treated for eight weeks either with calcium alone or with calcium plus vitamin D
这和美国的典型值一样，治疗8周，部分只用钙，部分是钙+维生素D
Modest dose eight hundred international units So，that was a pretty good dose for people back then
适度剂量 800国际单位，这在当时算不错的剂量了
Back then, only eight years ago, nine years ago
当时，其实也就八九年前
Now it's known that calcium lowers blood pressure
钙能降低血压
We don't use it for the treatment hypertension because it doesn't lower it enough
这不用于高血压治疗，因为降低程度不够
but at a population level that's been clearly established
不过就公共健康而言这显然有用
that you lower blood pressure with calcium usefully as a matter of fact
补钙确实能降低血压
but not therapeutically useful. So there's a difference there
只是不用于治疗而已，这有差别
So the question was not so much that calcium do it
因此问题不是钙降血压这一事实
but there's vitamin D add something to the calcium which would be better than the calcium alone
而是维生素D+钙是否比只用钙要好
and what we have is simply an 8-week trial
这只是简单的8周试验
This is one of those acute effects that you can produce very early on
这个效果很快就能显现出来
The gray bars are the baseline values
灰色条形图是基线值
for the calcium only group, for the calcium + D group
左侧是只补钙，右边是钙+维生素D
And the open bars are the 8-week values at the end of the briefly treatment period
空心条形图是8周治疗后的值
5.7 millimeter of mercury drop from calcium alone
只补钙，降低5.7毫米汞柱，
which I think you would agree with me is useful from a public health standpoint but may not be enough if you're treating a patient with clear hypertension
大家肯定赞同，这对公共健康有用，但对高血压患者治疗却不够
So I guess I make that distinction
这有必要区别开
