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Hey there! Welcome to Life Noggin. Xanax is one of the most prescribed psychiatric medications in the United States.
大家好，欢迎来到大脑洞开的生命奇想！阿普唑仑是美国开得最多的精神药物之一。
It's the brand name for alprazolam, a drug used to manage anxiety and panic disorders.
Xanax是阿普唑仑的商标名，这是一种用于治疗焦虑和恐慌障碍的药物。
It has also been used to treat depression, PMS, and chronic pain. When used as prescribed, it can be very beneficial.
它也被用来治疗抑郁症，经前综合症和慢性疼痛。当按照规定使用时，它可以是非常有益的。
However, because of its calming effects, it is often misused to achieve a tranquil high.
然而，由于此药物的镇静作用，它经常被误用来实现一种平静的高潮。
And taking more than the prescribed dose, taking it more frequently, or taking it with other drugs or alcohol can be fatal.
过量食用这种药物，过于频繁食用它，或者将它和其它药物或酒精一块食用有时是会致命的。
In just the first half of 2008, this class of drugs accounted for the second highest amount of overdose deaths in the state of Florida.
仅仅在2008年的上半年，这类药物导致佛罗里达州第二高的药物过量致死人数。
Of these 392 deaths, Xanax was responsible for nearly 300 of them.
在这392例死亡中，有近300例是阿普唑仑造成的。
The number of people admitted to addiction treatment facilities in the U.S. for Xanax use has rapidly increased.
美国因服用阿普唑仑致住院接受成瘾治疗的人数在急剧增加。
From 2006 to 2012, this number went from around 5,000 to about 29,500.
从2006年到2012年，这一数字从5000人左右增加到29500人左右。
And according to the 2013 National Survey on Drug Use and Health,
根据2013年全国药物使用和健康调查，
the abuse rate in those between the ages of 18 and 25 is nearly twice as high compared to people over 26.
18至25岁的人群中药物的滥用率差不多是超过26岁人群药物滥用率的两倍。
Xanax is a member of a group of medications called benzodiazepines.
阿普唑仑是苯二氮平类药物的一种。
These drugs affect the central nervous system - the brain and nerves - to decrease abnormal excitement in the brain and create a calming effect.
这些药物影响中枢神经系统——大脑和神经——以减少大脑中的异常兴奋，并产生镇静作用。
They do this by increasing the activity of a chemical, called gamma-aminobutyric acid or GABA, that inhibits brain activity.
他们通过增加一种叫做γ-氨基丁酸或伽马氨基丁酸的化学物质的活性来做到这一点，这种化学物质可以抑制大脑活动。
This creates less of a restraint on the brain's dopamine producers resulting in more dopamine,
这减少了对大脑多巴胺产生的限制，导致产生更多的多巴胺，
which controls the reward and pleasure centers in the brain.
多巴胺控制着大脑中的奖励和快乐中心。
This creates increased feelings of pleasure and decreased feelings of panic or anxiety.
这会增加快乐的感觉，减少恐慌或焦虑的感觉。
There are many potential side effects of this medication, ranging from headaches, drowsiness,
这种药物有很多潜在的副作用，比如头痛，嗜睡，
and nausea, to more serious ones like hallucinations, loss of coordination, and suicidal thoughts.
恶心，更严重的是幻觉，失去协调性，产生自杀念头。
Prolonged use can lead to dependence, and if stopped abruptly, patients can experience withdrawal or seizures.
长期使用阿普唑仑会导致依赖，如果突然停止使用，患者可能会出现戒断或癫痫发作。
Dependence occurs when your body builds up a tolerance for the effects of the drug,
当你的身体对药物的作用产生耐受性时，就会产生依赖性，
requiring a larger dose or an increased frequency of use to achieve the same effect it had when you started taking it.
这就需要更大的剂量或增加使用频率，以达到与开始服用时相同的效果。
This can develop into a physical dependency where your body doesn't function properly without it.
这可能会发展成一种身体依赖，没有它，你的身体就不能正常工作。
Dependence can often lead to addiction or a substance use disorder,
依赖往往会导致上瘾或药物使用障碍，
which is generally defined as compulsive drug use despite the harmful consequences.
这就是通常所说的强迫性用药，尽管这会产生有害的后果。
If you think you have an addiction, contact a treatment expert immediately.
如果你认为你有上瘾的情况，请立即联系治疗专家。
The Substance Abuse and Mental Health Services Administration provides a free referral helpline that can connect you with treatment centers, support groups, and community organizers.
药物滥用和精神健康服务管理局提供了一个免费的转诊热线，可以将你与治疗中心、支持团体和社区组织者联系起来。
Be safe and consult a doctor before taking any medication. This topic was highly requested by you guys,
在服用任何药物之前请注意安全并咨询医生。这期视频是在你们的强烈要求下制作的，
so you if you have any other drug that you want us to talk about, let us know in the comment section below.
所以如果您有任何其他药物想要我们讨论，请在下面的评论部分告诉我们。
Curious to know the effects of Adderall on the human body? Check out this video!
想知道安非他明对人体的影响吗？看看这个视频！
According to the National Institute of Drug Abuse,
根据国家药物滥用研究所，
taking prescription stimulants for reasons outside of treating ADHD or narcolepsy could lead to negative effects on your health, like heart problems or psychosis.
出于治疗多动症或嗜睡症之外的原因服用处方兴奋剂可能会对你的健康产生负面影响，比如心脏病或精神病。
Thank you so much for watching and liking this video!
非常感谢您观看并喜欢这个视频！
As always my name is Bloccko! This has been Life Noggin! Don't forget to keep on thinking.
我是宝高，这里是脑洞大开的生命奇想。思考不要停！
