1.It's not really my thing. 这不是我擅长的，这不是我喜欢的
Do you like Beijing opera? It's not really my thing.
你喜欢京剧吗？我不喜欢。

2.have a thing about sb/sth (informal) 莫名地喜欢或者讨厌
She's always had a thing about Peter.
她喜欢/讨厌Peter。

3.do things to me 使我十分激动；震撼了我
That song just does things to me.
一听到那首歌我就很激动。
This movie really does things to me.
这部电影让人觉得很震撼。

4.a thing 任何东西（用于否定句，加强语气）
I haven't got a thing to wear!
我没有一件能穿的衣服！
I haven't got a thing to do.
我没一件事可做。
Ignore what he said -- it doesn't mean a thing.
别管他说什么，他那都是瞎说。