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A global epidemic of cancer among people younger than 50 could be emerging

When cancer strikes an adult under the age of 50, doctors call it an early-onset case. These cancers at younger ages are becoming more common.

A new review of cancer registry records from 44 countries found that the incidence of early-onset cancers is rising rapidly for colorectal and 13 other types of cancers, many of which affect the digestive system, and this increase is happening across many middle- and high-income nations.

The review’s authors say the upswing in younger adults is happening in part because of more sensitive testing for some cancer types, such as thyroid cancer. But testing doesn’t completely account for the trend, says Ogino, a professor of pathology at Harvard.

Ogino says the spike is due to an unhealthy stew of risk factors that are probably working together, some of which are known and others that need to be investigated.

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