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PBS高端访谈:奥施康定制造商普度将停止向医生推销阿片类药物

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Hari Sreenivasan: This week, the maker of Oxycontin, announced it is ending its marketing operation for the powerful opioid. Purdue Pharma is not giving up selling the highly profitable drug, but it will stop sending reps to doctors offices to drive sales of the addictive painkiller. Back in 2007, Purdue pleaded guilty to criminal charges of misleading the public about Oxycontin's addictive qualities and agreed to a civil penalty of nearly $635 million. This week's decision comes as Purdue and other opioid manufacturers are facing lawsuits from some 400 cities and states alleging they fueled addiction by misrepresenting the risks. Could Purdue's move change the course of America's opioid crisis? Lev Facher is a reporter with STAT News and joins me from Washington, D.C. tell me how significant this is?

Lev Facher: Symbolically this is huge. This is the company that really changed the paradigm for opioid use in the 1990s by aggressively marketing it to prescribers. The fact that Purdue has decided it's no longer going to go into doctor's offices an push this drug is really symbolic of where the country currently is in terms of considering the opioid epidemic a public health crisis and in terms of recognizing the potential harmful characteristics of drugs like Oxycontin.
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Sreenivasan: What is the correlation between marketing them less and less of them being available on the street?

Lev Facher: Obviously, marketing drugs less should correspond to fewer sales. That said, this is not really a preemptive move. This is after years of declining Oxycontin sales. The Centers for Disease Control and Prevention issued recently new and much stricter guidelines for opiod prescription, so prescriptions are down, public awareness of the addictive qualities of these drugs is way up. And while there's still legitimate medical need and while prescriptions are going to continue, this is a move that more corresponds to a decline in sales than one that should fuel one.

Hari Sreenivasan: What are the factors that can actually decrease opioid consumption overall, or over prescription? It seems there is a tremendous amount of power in the hands of the insurance companies that choose to say that it's okay to prescribe these and that we'll pay for them.

Lev Facher: Yeah, and both insurance companies and public health providers like medicaid and medicare have taken steps, a variety of steps recently to reduce prescriptions and increase incentives to prescribe nonopioid, non-addictive pain killers. But again the marketing, I think, is less of something that is going to drive fewer prescriptions and more on Purdue's front on something that is meant to really change the narrative. They've been taking out full page ads in newspapers. They have been really trying to get out in front of the fact that they are increasingly viewed as a culprit. You mentioned the settlement in 2007. They are in talks to settle many of those other lawsuits from states and municipalities that you mentioned. So in terms of marketing, it's unclear of what level of impact that's going to have on prescription levels. But this comes amid really a sea change in the way physicians are prescribing opioids to begin with. And that has been happening over the last several years along with actions from the drug enforcement agency. A lot of different government agencies that are really taking steps to make sure that these drugs are used much less liberally.

Hari Sreenivasan: All right, Lev Facher of STAT News joining us from washington, thanks so much.

Lev Facher: Thanks, Hari.

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重点单词   查看全部解释    
correspond [.kɔris'pɔnd]

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vi. 符合,通信,相当

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symbolic [sim'bɔlik]

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n. 代号 adj. 象征的,符号的

 
insurance [in'ʃuərəns]

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n. 保险,保险费,安全措施

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control [kən'trəul]

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n. 克制,控制,管制,操作装置
vt. 控制

 
epidemic [.epi'demik]

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n. 传染病,流行病
adj. 流行的,传染性

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narrative ['nærətiv]

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n. 叙述,故事
adj. 叙事的,故事体的

 
painkiller ['pein.kilə]

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n. 止痛药

 
guilty ['gilti]

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adj. 有罪的,内疚的

 
prescribe [pris'kraib]

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vi. 规定,开药方
vt. 规定,命令,开处

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overall [əuvə'rɔ:l]

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adj. 全部的,全体的,一切在内的
adv.

 

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