376. The boy's foolish question irritated his mother who was busy with housework and had no interest in talking.
短语be busy with也意为“忙于”，相当于be engaged in. have no interest in doing sth.意为“没兴趣做某事”。irritate sb.是“激怒某人，惹恼某人”的意思。
1)She no longer takes any interest in that book.
2)What interested her most was the longitude line.