释义：

have a problem 有问题，有不满

正如字面含义那样，表示有问题，即不满等情绪，如果没有任何不满或问题的话可以说 have no problem with。

例句：

I have no problem with that.
我没问题。
What's with you? Do you have a problem with me?
你怎么了？你对我有不满？
Do you have a problem with that?
你对那个不满吗？

对话：

A: I have a problem.
我有点问题。
B: Really? What happened?
真的？怎么了？