Six years after their last adventure, stoner pals Harold (John Cho) and Kumar (Kal Penn) have grown apart and found new friends. As each is busy making holiday preparations, a mysterious package mistakenly arrives on Kumar's doorstep. Unfortunately, Kumar's attempt to redirect the package to Harold goes up in smoke -- along with a prize Christmas tree belonging to Harold's father-in-law. The pair's journey across New York City to find a replacement tree threatens to blow Christmas Eve sky-high.