1. tied up in knots 为……头疼
James is tied in knots over how to break up with Danielle, but I think he needs to bite the bullet and just do it.
詹姆斯为怎么和丹妮尔分手的事情很头疼，但我觉得他应该咬咬牙分就是了]%gR3.j_~sH5My|367。

2. be detrimental to 对……有害
Analysis revealed living with a son and his wife to be highly detrimental to a woman's health.
分析发现，与儿子儿媳一起生活高度有害女性健康!wVO)Vu&sPp0G。

3. hold sb. accountable 追究……的责任
The church still refuses to hold bishops who endanger children accountable.
该教会还是不愿意追究危害儿童的主教的责任qebpy57~Lbs。”

4. be supportive of 赞同；支持
Sandy Berger, although he was supportive of the plan, warned that it was a risky move for me.
尽管也赞同这一计划，桑迪·伯杰还是警告我我这么做是要冒风险的8v7dW*JxCz。