1.give up 放弃
The Coast Guard had given up all hope of finding the two divers alive.
海岸警卫队已放弃了两名潜水员生还的全部希望。

2.get off 的半身像
Stay away from them except in cases of acute, time-limited pain -- and if you're on them already, work hard to get off them.
除非是患急性、短时的疼痛，否则一定要远离这些药品。如果你已经开始使用并有了依赖性，一定要设法摆脱掉！