mean 吝啬的;刻薄的;破旧的;残忍的
The little girls had locked themselves in upstairs because Mack had been mean to them...
小姑娘们把自己锁在楼上，因为麦克对她们很刻薄。
Not stupid. You're meaner than I thought.
不是白痴，是很恶劣

give up 放弃; 投降
But some mountaineers do not give up.
但是一些登山家并没有放弃。
Don't give up on yourself.
你自己造成不要放弃自己。